I2I Online Seminar with Katie Witkiewitz: Precision medicine approaches to the development and dissemination of treatments for alcohol and substance use disorders

Date: Apr 26, 2019 1:00 PM in Eastern Time

Abstract: There are multiple effective interventions for alcohol and other substance use disorders, however, effect sizes versus control conditions tend to be small. For example, our work has found mindfulness-based interventions to be more efficacious and effective than “gold standard” treatments (cognitive behavioral treatment, 12-step approaches) in the treatment of substance use disorder with small effect sizes. The current presentation will discuss the development and dissemination of mindfulness-based interventions and recent attempts to identify which individuals are most likely to respond best to mindfulness-based interventions based on different phenotypic profiles. The presentation will also highlight similar research in the area of medications for alcohol use disorder and how methodological approaches can be used to phenotype individuals to pursue precision medicine hypotheses. Future directions that include rigorous tests of precision medicine hypotheses and adaptive designs will also be discussed.

Katie Witkiewitz is a Regents’ Professor of Psychology and Scientist at the Center on Alcoholism, Substance Abuse, and Addictions at the University of New Mexico. She has studied mindfulness-based interventions for substance use disorder since 2001. Dr. Witkiewitz also has expertise in quantitative methods and is interested in how the methodology can inform precision medicine for alcohol and other substance use disorders.

Register here.

 

April 22, 2019 | Michael Otto, PhD Presenting on Context Matters: Internal Context, Distress Intolerance, and the Application of Psychosocial Treatment

Michael W. Otto, Ph.D., is Professor in the Department of Psychological and Brain Sciences and Senior Fellow in the Institute for Health System Innovation and Policy at Boston University. He has had a major career focus on developing and validating new psychosocial treatments, with a focus on treatment refractory populations including those with anxiety, bipolar, and substance use disorders. His work includes a translational research agenda investigating brain-behavior relationships in therapeutic learning, including the use of novel strategies to improve the consolidation of therapeutic learning. Dr. Otto’s focus on hard-to-treat conditions and principles underlying behavior-change failures led him to an additional focus on health-behavior promotion, including investigations of addictive behaviors, medication adherence, sleep, and exercise. Across these behaviors, he has been concerned with cognitive, attention, and affective factors that derail adaptive behaviors. Dr. Otto has published over 400 articles and over 20 books spanning his research interests, and he Dr. Otto was identified as a “top producer” in the clinical empirical literature, an ISI Highly Cited Researcher, and winner of the 2019 Distinguished Scientific Contributions to Clinical Psychology award from APA Division 12. His past leadership positions include serving as President of the Association of Behavioral and Cognitive Therapies, and President of Division 12 of the American Psychological Association.


Calling Info:

Meeting URL: https://meetings.webex.com/collabs/#/meetings/joinbynumber

Meeting Number: 191 616 728

If using phone line for audio/teleconferencing: +1-415-655-0001 and enter the meeting number, once prompted

If using audio from your computer: Once you join the meeting, select? Call Using Computer? to automatically connect

 

Ideas to Interventions (I2I)

Ideas to interventions (I2I) is a new community, formed in conjunction with the National Cancer Institute (NCI). The I2I community is a first step toward achieving the goal of building and nurturing a network of researchers who are interested in “early-phase behavioral translation research,” – the translation of novel ideas and approaches from basic behavioral and social sciences research into new strategies to address pressing clinical or public health problems. The primary objective is to broaden, deepen and build new connections among individuals interested and engaged in developing new and potentially more effective approaches to behavioral health problems, including researchers, clinicians, patients and the public.

 

This website (https://i2ihub.org/) will host information for members, and potential members, to learn more about each other’s work.

 

 

 

RFA-DK-18-007, Establishing a Cohort to Clarify Risk and Protective Factors for Neurocognitive Complications of Pediatric Type 1 Diabetes (T1D)

Funding Opportunity Purpose: This FOA invites applications for planning cooperative agreements (U34) for a national, multisite, observational cohort study to prospectively examine the risk and protective factors for neurocognitive complications of pediatric type 1 diabetes (T1D; onset approximately ages 5-10 years) and a comparison sample. The U34 is designed to: 1) Permit early peer review of the rationale for the proposed cohort study; 2) Permit assessment of the study design; and 3) Provide support for the development of essential elements required for the design and conduct of the cohort study and the management and analysis of the study data. Consultation with NIDDK scientific staff is strongly encouraged prior to the submission of the U34 application.

 

Application Due Date: April 11, 2019, by 5:00 PM local time of applicant organization

 

February 26, 2019 | Linda Collins PhD Presents: Introduction to the Multiphase Optimization Strategy for Building Better Behavioral and Biobehavioral Interventions

Linda M. Collins, Ph.D., is Distinguished Professor of Human Development & Family Studies at the Pennsylvania State University, United States. She is also Director of The Methodology Center, an interdisciplinary research center devoted to the advancement and dissemination of quantitative methods for applications in drug abuse prevention and treatment, as well as other areas in the behavioral sciences. Dr. Collins’s research interests include the multiphase optimization strategy (MOST), an engineering-inspired methodological framework for optimizing and evaluating behavioral, biobehavioral, and biomedical interventions. The objective of MOST is to improve intervention effectiveness, efficiency, economy, and scalability. Dr. Collins is currently collaborating on research applying MOST to develop optimized behavioral interventions in the areas of smoking cessation, weight loss, prevention of excessive drinking and risky sex in college students, and HIV services. Her research has been funded by NIDA, NCI, NIDDK, and NIAAA.

Calling Info:

Meeting URL: https://meetings.webex.com/collabs/#/meetings/joinbynumber

Meeting Number: 191 366 190

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March 18, 2019 | Pamela Herd PhD Presents: Social and Population Health Science Approaches to Understanding the Human Gut Microbiome

Event Date: March 18, 2019 at 2pm EST

The microbiome is now considered our “second genome,” with potentially comparable importance to the genome in determining human health. There is, however, a relatively limited understanding of the broader environmental factors, particularly social conditions, that shape variation in human microbial communities. Fulfilling the promise of microbiome research—particularly the microbiome’s potential for modification—will require collaboration between biologists and social and population scientists. For life scientists, the plasticity and adaptiveness of the microbiome calls for an agenda to understand the sensitivity of the microbiome to broader social environments already known to be powerful predictors of morbidity and mortality. For social and population scientists, attention to the microbiome may help elucidate nagging questions as to the underlying biological mechanisms that link social conditions to health. We outline key substantive and methodological advances that can be made if collaborations between social and population health scientists and life scientists are strategically pursued, as well as provide a recent example of just such a collaboration.

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Data Manager Position at Columbia University Medical Center

The Data Manager will lead the data management team at the Center for Behavioral Cardiovascular Health. S/he will have primary responsibility for database programming, data integrity, and descriptive data analysis of a number of ongoing cohort studies and behavioral trials. The Candidate will work with research project staff and investigators to ensure that both electronic and non-electronic data are stored in an IRB/HIPAA compliant manner, create SPSS/SAS files for data analysis, merge information from multiple data files, compute summary scales, develop and execute quality control procedures to enhance the integrity of the data, coordinate data core activities with regards to progress report deadlines and abstract submission deadlines, perform basic statistical analyses and assist in interpreting and presenting results, while also supervising data management staff. The candidate will interact with investigators and staff at Columbia University and at other sites and report to CBCH principal investigators.
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