Addressing the Complexity of Refractory Conditions with Mechanism-Targeted Psychosocial Intervention
Monday, May 22, 2017
2:00-3:00 pm (EST)
Traditional empirically based psychosocial treatments have been associated with considerable efficacy, especially with anxiety- and mood-related outcomes. However, sizable subgroups of individuals remain refractory to improvement. Recent advances in classification, experimental therapeutics, and precision medicine offer promise for isolating mechanisms common to many pathological conditions and developing targeted interventions, as a result. However, complex conditions with multiple overlaying dysfunctions may require multi-componential treatments to produce clinically significant and pervasive outcomes. Emotion Regulation Therapy (ERT) is an affect science based, mechanism-targeted, psychosocial intervention for chronic anxiety and mood disorders characterized by high levels of transdiagnostic negative self-referencing processes (i.e., worry, rumination, self-criticism), which are associated with poor outcome. Efficacy and preliminary mechanism data for ERT will be presented with the goal of illustrating the need for both inductive (e.g., experimental therapeutics) and deductive (i.e., honed psychosocial treatment) approaches to targeting mechanisms and improving clinical outcomes.